By Richard S. Stern, R. McKie
Complete textual content on epidemiology and prevention of pores and skin ailments. For dermatologists, epidemiologists, and trainees. eighty members, 10 U.S. DNLM: dermis Disease--prevention & keep watch over.
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This is particularly important in severe and progressive conditions such as type I SMA where NIV may be used, at best, to reduce morbidity associated with acute chest infection and palliate symptoms. indd 34 Further reading Bushby K, Bourke J, Bullock R, Eagle M, Gibson M, Quinby J. The multidisciplinary management of Duchenne muscuar dystrophy. Current Paediatrics 2005; 15: 292–300. Chatwin M, Bush A, Simonds AK. Outcome of goaldirected non-invasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type I.
Cor pulmonale develops in those who are chronically hypoxaemic. • Copious endotracheal secretions, aspiration and tracheomalacia and/or bronchomalacia are common. • Feeding difficulties and aspiration are common. • Failure to thrive. • Osteopenia and fractures can occur due to severe metabolic bone disease. 13 Chest radiograph of a 25-week infant with a patent ductus arteriosus demonstrating widespread consolidation following a pulmonary haemorrhage. indd 21 • • • • • • small hazy lung fields in those least severely affected; large airway collapse; persistent atelectasis; interstitial shadows; lobar hyperinflation; gross cystic abnormalities.
Wang CH, Finkel RS, Bertini E, Schroth M, Simonds A, Wong B, Aloysius A, Morrison L, Main M, Crawford TO, Trela A. Consensus statement for standard of care in spinal muscular atrophy. J Child Neurol 2007; 22: 1027–49. 25/08/2011 16:20 Chapter 4 37 Interstitial lung disease Andrew Bush, Andrew G. Nicholson Introduction These are rare conditions, and few centres see more than a handful of cases per year. The spectrum of diagnoses is much wider than that of adult interstitial lung disease (ILD); and they occur in the context of the growing and maturing lung and immune system, which may affect the manifestations of a particular disease.