By Harry Gelboin
Polycyclic Hydrocarbons and melanoma, quantity 1: setting, Chemistry, and Metabolism brings jointly info from many varied disciplines within the environmental, chemical, organic, and clinical sciences to supply a complete account of the hyperlink among polycyclic fragrant hydrocarbons (PAHs) and melanoma.
This quantity includes 19 chapters divided into seven sections in accordance with the next subject matters: power resources; Environmental incidence and tracking; Tobacco Carcinogenesis; Chemistry, Carcinogenicity, and thought; Metabolism and Activation; Enzymology; and Pharmacokinetics. the 1st 3 chapters specialize in the strength resources, prevalence and surveillance, and environmental tracking of PAHs. The dialogue then turns to the hyperlink among smoking and melanoma; the carcinogenicity of 5-methylchrysene; synthesis and reactions of diol epoxides and comparable metabolites of carcinogenic hydrocarbons; and enzymes of oxygenation. the ultimate bankruptcy is dedicated to the pharmacokinetics of chemically reactive metabolites.
This e-book should be of curiosity to investigators and educators fascinated by clinical points of PAH examine; govt officers and elected representatives in addition to leaders who needs to confront and remedy the issues relating to PAHs; and others in a variety of fields reminiscent of chemistry, environmental technological know-how, biochemistry and enzymology, pharmacology, molecular and cellphone biology, and genetics.
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Sample text
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