Ciba Foundation Symposium - Interferon by G.E.W. Wolstenholme; & Maeve O'Connor (Editors)

By G.E.W. Wolstenholme; & Maeve O'Connor (Editors)

Chapter 1 Chairman's commencing feedback (pages 1–3): M. G. P. Stoker
Chapter 2 mobile occasions previous Interferon Formation (pages 4–17): D. C. Burke, J. J. Skehel, A. J. Hay and Shan Walters
Chapter three The Systemic Induction of Interferon (pages 19–38): Monto Ho, Bosko Postic and Yang H. Ke
Chapter four Statolon, as an Inducer of Interferon (pages 39–49): W. J. Kleinschmidt and L. F. Ellis
Chapter five Interferon Induction in Mouse and guy with Viral and Non?Viral Stimuli (pages 50–63): Thomas C. Merigan
Chapter 6 an easy approach for the Mass construction of Human Interferon: The Human Amniotic Membrane (pages 64–77): Charles Chany, Francoise Fournier and Ernesto Falcoff
Chapter 7 Purification of Interferons (pages 78–94): okay. H. Fantes
Chapter eight at the obvious Heterogeneity of Rabbit Interferons (pages 95–109): Robert R. Wagner and Thomas J. Smith
Chapter nine reviews at the Mechanism of motion of Interferon (pages 110–127): Wolfgang okay. Joklik
Chapter 10 The Mode of motion of Interferon (pages 128–142): P. De Somer and C. Cocito
Chapter eleven reports on Interferon motion (pages 143–159): J. A. Sonnabend, E. M. Martin and E. Mecs
Chapter 12 The Mechanism of motion of Interferon (pages 160–185): Hilton B. Levy and William A. Carter
Chapter thirteen a few Determinants of the Interferon?Induced Antiviral kingdom (pages 186–203): S. Baron, C. E. Buckler and F. Dianzani
Chapter 14 Of Mice and males: reports with Interferon (pages 204–217): N. B. Finter
Chapter 15 impact of alternative Carcinogenic brokers at the creation of Interferon in Tissue tradition and within the Animal (pages 218–239): Edward De Maeyer and Jaqueline De Maeyer?Guignard
Chapter sixteen The influence of Interferon arrangements on pal Leukaemia in Mice (pages 240–261): I. Gresser, J. Coppey, D. Fontaine?Brouty?Boye, E. Falcoff, R. Falcoff, F. Zajdela, C. Bourali and M. T. Thomas

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Eventual conclusive identification of statolon as a virus would mean that a non-mammalian virus is capable of stimulating the production of interferon. A recognition mechanism that is stimulated into operation in 44 W. J. K L E I N S C H M I D T A N D L . F. E L L I S cells on infection by a mammalian virus as a means of defence against that virus is apparently also triggered into action by the virus-like statolon particles. Not only has the finding of these particles with virus morphology added to the interferon story, but should these particles prove to be viruses, new studies with moulds, such as the introduction of genetic material via transduction, may also have been made feasible.

None” signifies that no vaccine was given. Each titre represents the mean obtained $om two to six animals bled two hours after endotoxin or four hours after virus. 10 pg. endotoxin or On the other hand, pretreatment of mice with cytomegalovirus reduced interferon induction by Ncwcastle disease virus (Osborn and Medearis, 1967). It has been shown by Wagner, Iio and Hornick (1963) that systemic virus infections such as sandfly fever and dengue, unlike many bacterial infections, are associated with decreased RE function as measured by the clearance of radioactively labelled aggregated albumin.

Din. , 44, 1059. , and BREINIG,M. K. (1965). Pror. Snr. e-vp. Bid. , 119, 1227-1232. , and POSTIC, B. (19672). f Man, pp. 632-649. C. : PAHO/WHO Scientific Publication 147. , and POSTIC, B. (19676). , 214, 123-1231. KE, Y. , and MEXICAN, T. C. (1966). Nufirre, Lord, 211, 541-542. KE, Y. , SINGER, S. , and Ho, M. (1966). Proc. SOC. cxp. Biof. , 121, I 81-1 83. KONO,Y. (1967). Proc. Soc. exp. Biol. , 124, 155-160. , and Ho, M. (1965). Virofogy,25, 162-166. , and BRAUN, W. ) (1964). BacteriulEiidotoxiru.

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