Chapter 1 Chairman's beginning comments (pages 1–4): Professor R. E. Tunbridge
Chapter 2 Diabetes in a Village neighborhood (pages 5–24): Joan B. Walker
Chapter three Spontaneous Diabetes Mellitus within the chinese language Hamster, Cricetulus griseus. IV. Genetic features (pages 25–48): George Yergaman
Chapter four The Endocrine Pancreas in Human and Experimental Diabetes (pages 49–74): Robertson F. Ogilvie
Chapter five Pancreatic Beta mobile (pages 75–88): Paul E. Lacy
Chapter 6 Panel dialogue on Biosynthesis and Secretion of Insulin: Biosynthesis of Insulin (pages 89–94): ok. W. Taylor
Chapter 7 Insulin Biosynthesis and Glucose Metabolism in Islet arrangements (pages 95–98): Albert E. Renold
Chapter eight Secretion of Insulin triggered by way of Leucine in fit topics (pages 99–106): Stefan S. Fajans, John C. Floyd, Jr. Ralph F. Knopf and Jerome W. Conn
Chapter nine fee of unlock of Insulin in vitro (pages 107–121): P. J. Randle
Chapter 10 Immunological reviews with Homologous and Heterologous Pancreatic Insulin within the Cow (pages 122–139): Albert E. Renold, Stuart Soeldner and Jurgen Steinke
Chapter eleven Plasma Insulin in Diabetes (pages 140–155): C. N. Hales
Chapter 12 Insulin Antagonism: primary issues (pages 156–191): David M. Kipnis and Martin F. Stein
Chapter thirteen The Glucose Fatty Acid Cycle and Diabetes Mellitus (pages 192–216): P. J. Randle, P. B. Garland, C. N. Hales and E. A. Newsholme
Chapter 14 Synalbumin Insulin Antagonism and Diabetes (pages 217–239): J. Vallance?Owen
Chapter 15 Pituitary Polypeptide Antagonists of Insulin (pages 240–249): J. Bornstein, Deirdre Hyde and ok. J. Catt
Chapter sixteen Peripheral motion of Insulin Diabetes Mellitus and its Relation to the Aetiology of Diabetes Mellitus (pages 250–281): W. J. H. Butterfield
Chapter 17 The Biochemistry of Blood Vessels (pages 282–300): Helen Muir
Chapter 18 The Glomerular Lesion in Idiopathic and Secondary Diabetes (pages 301–314): M. ok. Macdonald and J. T. Ireland
Chapter 19 Pathophysiology of Microangiopathy in Diabetes Mellitus (pages 315–344): Searle B. Rees, Rafael A. Camerini?Davalos, James B. Caulfield, Oscar Lozano?Castaneda, Alfredo Cervantes?Amezcus, Jan Taton, Daniel Pometta, Jorge P. Krauthammer and Alexander Marble
Chapter 20 Panel dialogue at the function of the Pituitary in Human Diabetes and its problems within the Aetiology of Diabetes Mellitus: The Anterior Pituitary (pages 345–347): J. Bornsteiy
Chapter 21 The Roe of the Pituitary in Human Diabetes (pages 348–353): R. Luft
Chapter 22 The impact of Yttrium?90 Pituitary Implantation on Diabetic Retinopathy (pages 354–390): G. F. Joplin
Chapter 23 final feedback (pages 391–392):
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Extra resources for Ciba Foundation Symposium - Aetiology of Diabetes Mellitus and its Complications (Colloquia on Endocrinology), Volume 15
GREEN,M. , and GAGNON, H. J. (1963). ), 197, 396. LAWE, J. Arch. , 73, 166. ,and YERGANIAN, G. Proc. Soc. exp. Bid. ),100, 810. ,and YERGANIAN, G. (1961~). Diabetes, 10, 12. ,and YERGANIAN, G. Diabetes, 10, 19. ,and YERGANIAN, G. ]. , 31, 861. ,COHEN,M. , and YERGANIAN, G. , 33, 14. YERGANIAN, G. Genetics, 37, 838. YERGANIAN, G. nut. , 20, 705. YERGANIAN, G. In Methodology of Mammalian Genetics, p. 469, ed. Burdette, W. J. San Francisco: Holden-Day. YERGANIAN, G. , ed. Worden, A. N. and Lane-Petter, W.
1961]. Diabetes, 10, 41)done in Melbourne with Dr. Margaret Sanders we found essentially the same as Dr. Fajans. This study was done on rather a small scale but we were very conscious of the age problem in the controls, because we originally thought we would use patients recovering in bed from fractured necks of the femur, there being large numbers of such cases in our hospitals. Over 75 per cent of these people who were over 60 had abnormal curves and abnormal cortisone tolerances, so we put them in groups according to age-+zo,20-40, 40-60 years-with about 3 0 in each group.
Randle: You say that you can visualize the chromosomes. Have you obscrved any actual abnormalities of chromosomes in the diabetic strain? Yerganiarr:No, they all appear quite normal. Fujans: You score the animals as diabetic or non-diabetic according DISCUSSION 45 to symptomatology and glycosuria. Might it not be possible that you have missed some mild diabetics,just as latent diabetic humans are discovered only by the glucose tolerance test ? Would that not influence your scheme of the genetics of the disease ?