Carbohydrate Mimics: Concepts and Methods by Yves Chapleur

By Yves Chapleur

Carbohydrate Chemistry and Glycobiology have witnessed a speedy growth over the last few years with the improvement of various new, innovative and effective syntheses which offer extra perception into constructions and organic interactions of glycoconjugates. Glycosylation reactions are general within the synthesis of prescription drugs and bio-active compounds. In biology and drugs oligosaccharides play a critical function in immuno-stimulation, melanoma or allergic responses. Glycoscience is a really instructive instance of the way one universal subject of curiosity stimulates either chemistry and biology to jointly open clinical frontiers.This synergy is made seen during this paintings. 3 prime specialists within the fields of Glycochemistry and Glycobiology have invited a number of well known authors to supply a finished evaluation of the new advances and findings in Glycoscience. This four-volume instruction manual provides an built-in and state of the art view, and covers all chemical features, akin to syntheses and research of carbohydrates and oligosaccharides, in addition to the organic position and job of oligosaccharides and carbohydrate/protein interactions.

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Brain ................................................................. Enzymatic Reactions of KS Biosynthesis ........................... Metabolic Control of KS Synthesis ................................. Acknowledgments ................................................... References ........................................................... 407 The Biosynthesis of GPI Anchors .................................... Yasu S. Serrano. and Paul T. Englund Introduction .........................................................

And Pathologies .............................. 736 Summary .............................................................

5 Nerve Growth Cone Guidance ...................................... Cell Adhesion ........................................................ Other Possible Roles of KSPGs ..................................... Acknowledgment .................................................... References ............................................................ 44 Developmental and Aging Changes of Chondroitin/Dermatan Sulfate Proteoglycans ........................................................ 729 J . Michael Sorrell.

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