British National Formulary by Joint Formulary Committee

By Joint Formulary Committee

The British nationwide Formulary (BNF) is your crucial reference booklet for prescribing, dishing out, and administering drugs.

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Cyclizine is given in a dose of 50 mg up to 3 times daily by mouth. It is used for nausea and vomiting due to BNF 66 mechanical bowel obstruction, raised intracranial pressure, and motion sickness. 5–25 mg twice daily (6-mg tablets available from ‘special-order’ manufacturers or specialist importing companies, see p. 1059). For the dose by subcutaneous infusion, see below. Dexamethasone 8–16 mg daily by mouth can be used as an adjunct. Antiemetic therapy should be reviewed every 24 hours; it may be necessary to substitute the antiemetic or to add another one.

Drugs given shortly before term or during labour can have adverse effects on labour or on the neonate after delivery. The BNF identifies drugs which: . may have harmful effects in pregnancy and indicates the trimester of risk . 00–17:00 Monday to Friday; urgent enquiries only outside these hours). The information is based on human data, but information from animal studies has been included for some drugs when its omission might be misleading. Prescribing in breast-feeding Breast-feeding is beneficial; the immunological and nutritional value of breast milk to the infant is greater than that of formula feeds.

G. bromocriptine). the amount of drug or active metabolite of the drug delivered to the infant (dependent on the pharmacokinetic characteristics of the drug in the mother); The BNF identifies drugs: . that should be used with caution or are contraindicated in breast-feeding; . the efficiency of absorption, distribution, and elimination of the drug by the infant (infant pharmacokinetics); . that can be given to the mother during breastfeeding because they are present in milk in amounts which are too small to be harmful to the infant; .

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