Alkaloids: Biochemistry, Ecology, and Medicinal Applications by Margaret F. Roberts

By Margaret F. Roberts

Not because the past due Seventies has a unmarried paintings offered the biology of this heterogenous staff of secondary alkaloids in such intensity. Alkaloids, a distinct treatise that includes leaders within the box, offers either the historic use of alkaloids and the newest discoveries in

  • the biochemistry of alkaloid construction in vegetation
  • alkaloid ecology, together with marine invertebrates, animal and plant parasites, and
  • alkaloids as antimicrobial and present medicinal use

. Highlights comprise chapters at the chemical ecology of alkaloids in host-predator interactions, and at the compartmentation of alkaloids synthesis, shipping, and garage. large cross-referencing in tabular structure makes this quantity a great reference.

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Extra resources for Alkaloids: Biochemistry, Ecology, and Medicinal Applications

Example text

Arriving at the island of Circe, they were offered wine that was mixed with Mandragora (which has been appropriately named "Circaia" ) and other solanaceous plants containing tropane alkaloids (for a more detailed account, consult sections on Atropa, Datura, Hyoscyamus , and Mandragora). The effects were hallucinations, suggesting that they were pigs. But Ulysses was as clever as Circe and had used the plant Moly (which was given to him by Hermes) as an antidote; so Circe had no power over Ulysses.

Vulparia, and other aconites accumulate the diterpene alkaloid aconitine (9) and related compounds in all parts of the plant. Because aconitine is highly lipophilic, it can be resorbed even through the skin. Aconitine reduces the secretion of acetylcholine presynaptically and activates Na" channels and thus leads to rapid paralysis 18 Michael Wink aconitine 9 and anesthesia. Because of these properties, extracts of aconite were employed as arrow poisons by early man in Europe, Alaska, and Asia.

Many other alkaloids and alkaloid-producing plants have been discovered to possess euphoric, psychomimetic and hallucinogenic properties (Schultes and Hofmann, 1980, 1987). , cocaine (8), reserpine (7)]. The hallucinogenic properties of plants must have puzzled early man and it is plausible that corresponding descriptions found their way into mythology. Female gods Michael Wink 16 N, N-dimethyltryptamine 6 7 have been described very early in this context. One of them is Kybele, the goddess of animals , mountains, and medicine.

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